Some will say no. Some will say yeah. I say yeah, but not the Nyko Intercooler. Try a different brand, the Pelician, since it draws power through the USB port instead of directly from power like Nyko Intercooler does. I had good time with Nyko Intercooler until it recently shut down after 10-15 minutes repeatedly. So I removed the Nyko Intercooler and I have had no problems since. It also seems Microsoft has a better fan in the 360's that are in stores now, snice they will replace any console made before 2005 for free. So that leads me to assume any xbox360 made in 2006 should be running excellent.