What do you like to do? What would you say are your greatest strengths? Greatest weaknesses?
No degree is worth a damn if it isn't in line with your own interests, aptitudes and abilities.
That said: check out the Money magazine site, or Kiplingers', CNN, and similar places. Google "degrees in demand" and you might find some good information.
Also think about what lifestyle you want to have. High pressure, high financial rewards, or low-key, lower financial rewards? Where do you want to live, and what sorts of services are needed there? Do you want a portable career (teaching, nursing, financial advising, sales, journalism), or do you want to live someplace specific and know that there are a lot of jobs in that area? (Computer programming around big cities, for instance. Oil engineering around the Gulf coast states, especially Texas. Theater in one sort or another in New York, Washington, Chicago, San Francisco. Arts in Santa Fe, New Mexico. Just tossing out some examples here, obviously not an exhaustive list. )
Most important (and I will shout this one from the housetops!): do not go into debt!!! Too many students graduate tens or even hundreds of thousands of dollars in debt, then can't find a job, or feel forced to take a job that isn't quite what they wanted (high-pressure law firm vs. public interest law, for instance) because they are behind the 8-ball financially due to that load of debt.