Germany introduces cancer jab

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Germany introduces cancer jab

Young girls in Germany are to be vaccinated against the virus that causes cervical cancer.
Italian health officials have also recommended 12-year old girls are immunised against human papillomavirus.

The issue has been controversial as some parents fear a vaccine against a virus which effectively is sexually transmitted could promote underage sex.

Government advisors are considering whether the HPV vaccine should be introduced in the UK.

Gardasil, made by Merck and Sanofi Pasteur, offers protection against HPV types 16 and 18, which are responsible for 70% of all cervical cancers and types 6 and 11, which cause about 90% of cases of genital warts.

UK-based GlaxoSmithKline also has a HPV vaccine, called Cervarix, in development but which has not yet been licensed in Europe.

The Standing Commission for Vaccination at the Robert Koch-Institut in Germany has recommended the universal vaccination of girls aged 12 to 17 years, four months ahead of schedule.

Although boys can pass on HPV infection, the Commission has not recommended that they also receive the vaccine.

Gardasil was already available from pharmacies but the move means that state insurance companies will fund the cost of the course of three injections in teenage girls.

The Italian Ministry of Health announced that vaccination of 12 years old girls in Italy can start as soon as regional vaccination centres are prepared.

Sexually transmitted infection

Around 80% of sexually active women can expect to have an HPV infection at some point in their lives.

And cervical cancer kills 274,000 women worldwide every year, including 1,120 in the UK.

In an editorial published last year, The Lancet called for mandatory vaccination against HPV for girls in all EU member states once they are 11 or 12.

Some experts have raised concerns about the heavy promotion of the vaccine by companies involved.

A spokesperson for the Department of Health said introduction of HPV vaccination was currently under investigation by the Joint Committee on Vaccination and Immunisation.

A study in Manchester of parents attitudes to HPV vaccine and research by the Department of Health had shown that most parents have not heard of HPV and were not aware of the role of HPV in cervical cancer.

Parents had concerns about offering a vaccine that protects against a sexually transmitted infection to children at a young age and the sexual health issues that could arise.

BBC NEWS | Health | Germany introduces cancer jab
 
EU approves cervical cancer jab

EU approves cervical cancer jab

Cancerous cervical cells are detected through smear tests
The European Union has approved the cervical cancer vaccine Gardasil, which could prevent nearly 3,000 cancers each year in the UK alone.
An independent expert advisory committee to the Department of Health will now decide whether it should be made available on the NHS.

Gardasil, made by Merck and Sanofi Pasteur, is designed to be given to girls and women aged nine to 26.

It works against human papillomavirus, which can lead to cervical cancer.

Gardasil protects against cervical cancer caused by HPV strains 6, 11, 16 and 18, and also against genital warts.

The vaccine has been in fierce competition with a rival from UK-based GlaxoSmithKline, called Cervarix, which is still a year off the European approval stage.

HPV

Around 80% of sexually active women can expect to have an HPV infection at some point in their lives.

The vaccines have caused controversy over plans to give it to girls as young as nine, before they become sexually active.

Boys could also be vaccinated in the hope of eventually eradicating HPV.

Cervical cancer kills 274,000 women worldwide every year, including 1,120 in the UK.

No decisions will be taken until the main JCVI present their recommendations to ministers for consideration

A Department of Health spokeswoman

Trials suggest vaccinating all 12-year-old girls against HPV could cut deaths from the disease by 75%.

Women will soon be able to go along to clinics and request the jab at a cost of around £65 per dose. Three doses are usually given over six months.

But it is not yet clear whether the vaccine will be available on the NHS.

A Department of Health spokeswoman said: "We are currently seeking expert advice from the Joint Committee on Vaccination and Immunisation on the efficacy, safety and benefits that these new vaccines may offer."

She said that a JCVI subgroup had met in May 2006 to review all available information on HPV vaccines and would hold further meetings during 2006, reporting to the main JCVI committee once they have all the relevant information.

"No decisions will be taken until the main JCVI present their recommendations to ministers for consideration," she added.

Smear tests still necessary

Doctors stress that the vast majority of HPV cases do not go on to cause cervical cancer.

Women can protect themselves against HPV by not having unprotected sex and not smoking. They are also advised to have regular smears to check for the virus.

Professor Alex Markham of Cancer Research UK said: "If a national vaccination programme is introduced it will be vital that women continue to attend for cervical smears.

"We don't yet know if the vaccines are effective in women who may already have been infected with HPV, nor how long the immunity given by the vaccines lasts."

Gardasil has already been approved for use in the US, Mexico, Australia, Canada and New Zealand.

A spokesman from GSK said: "It's good news that the European authorities have approved it. This is the first of two vaccines that will be targeting cervical cancer. We hope to have a similar approval some time in the first half of 2007."

BBC NEWS | Health | EU approves cervical cancer jab
 
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