Bottesini

Ok. I didn't know you meant the one specific case.

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It's a joke Nathan!

Deafness

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Pinky

I don't believe the stem cell would cure for deafness. It will not work for profound deaf. I agree with Faire_jour's posted toward Deafdude. I doubt it he would get stem cell to cure for his deafness. Because he was born to profound deaf.

How about stem cell to cure for deafness to make against deaf culture?? That is same as deaf culture's against CI. I rather be deaf with CI period!

I don't mind to get stem cell to cure for my retina disease or get retinal implant. Not deafness! The stem cell is long time to study for deafness. I trust in God's will. The god sent me gift to have CI to hear.

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LEFT: Implanted: 6/12/09
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OneSided

OK Pinky

- RNL BIO Rescues a College Student from Autoimmune Hearing Loss[/url]

http://www.youtube.com/user/rnlbio#p...-A7LaM]YouTube - rnlbio's Channel[/url]

http://www.youtube.com/user/rnlbio#p...hUv7NI]YouTube - rnlbio's Channel[/url]

http://en.wikipedia.org/wiki/Mesenchymal_stem_cell

I emailed the manager director, in Han Hong and asked him a few questions about this experimental treatment for hearing loss. He told me he would get further information and get back to me. He explained that they used Mesenchymal stem cell, as appose to donated or embryonic stem cells. This does indeed sound promising but I have to air on the side of caution. More pioneers need to go and have follow ups before i would personally risk it.

Mr Hong also informed me that in terms of costs the "minimum is $5,000 excluding travel expenses" that about £3,000 which is not bad theoretically i could do that now but as i mention already its too early.

As to the new CI vs Stem cells everybody has their opinion which is better - for me Stem Cells are far superior as they give one natural hearing without a machine attached to their skull. But at the same time if a person has had CI for 5+ years and is content then good for them. Its a FREE choice at the end of the day.

DEAFDUDE!

The fathers talk about his daughters audiograms on the you tube links check them out. Secondly nobody knows if having stem cells will give your hearing as you were born deaf. So what people say here is ignorant advice all I can say is ask your doctor and find out I personally believe the human body is very good at adapting.


EDIT- I dont wont to offend anyone but there are NO subtitles in the you tube links

Bottesini

You are more likely to offend the people by saying everyone here is ignorant.

By the way, you can't spell. And apparently can't afford spell checker.

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It's a joke Nathan!

OneSided

Thanks

webexplorer

My apology for my mistake... He was on the TV a few days ago, and he is in a full recovery. I don't remember if he mentioned about his medicine on the television. If I see his show again or his story, I'll add the link here. Thanks for correcting me.

Bottesini

No problem. Biblical justice. Insult for insult. Hey, are we veering into RELIGION ??????????????????

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It's a joke Nathan!

webexplorer

Was Chloe born deaf? If she born hearing and later on become deaf, I assume that it is completely different probably because she has some stem-cells that are alive along with the dead ones in her cochlear. Probably, she got the candidate for the surgery. (I'm glad that her surgery is successful.) Am I correct?

OneSided

I believe she became deaf, so she must have been born hearing. Apparently "Chloe visited Dr. Won, a plastic surgeon in Los Angeles to harvest her fat tissue around her belly button in last June. Then the tissue was sent to the laboratory RNL BIO in Germantown, Maryland, where they isolated stem cells, put them in liquid nitrogen shipper and transported them to RNL BIO in Seoul, Korea. It took them a month to expand her stem cells to a sufficient amount enough to treat her hearing loss"

So the cells came from the fat around her belly button.

I might be wrong, but I think this means that most people can have this treatment as they used her own stem cells. Not only that they harvested them from fat tissue Which most people have.

Peanut

<------ Interested in stem cell too! I hope we keep getting more of the latest. Pre-lingually hoh, it would be awesome not having to wear hearing aids. Keep them coming.

hongjh

In this case, stem cells were injected intravenously. In general, stem cell effect is observed at peak in one to three month post treatment.

stemcellsdeaf

hi,
would be interesting for those who are interested in a cure using stem cells and have difficulty hearing what the video says, or we have problems with language, that someone made a transcript of the video. Is anyone interested in making a transcript or a summary of what the video says?
thanks

deafdude1

AllDeaf.com - View Single Post - Info on STEM CELLS from scientific source, my replies to you

faire_jour, webexplorer and others, see my replies to you. I remember you said in one of your posts that ill still be saying "soon" in 10 years. That time is now! Chloe's doctors recommended CI but she got stem cells instead and the improvement was way more! Plus she avoided the risk of surgery! She isn't even wearing HAs in the youtube video! Once more people follow Chloe in getting stem cells, I am next in line.

She has usher's type 1 and was born deaf and is going blind. She would get stem cells to restore her vision but is against stem cells for deafness. She used to be against CI too but is now very pro CI. I respect her choice for CI and ask that she respect our choice for stem cells for our deafness.

How much improvement as a minimum in your deaf ear is required before you go ahead? It could be alot longer before stem cells can get a profoundly deaf ear to near normal. I am expecting a partial improvement but not a complete cure anytime soon.

I wonder what time frame Mr. Hong has in mind when stem cells can reliably give at least 20db improvement and also when 100 pioneers will have gone ahead. As to the cost, I can definately afford that! Way cheaper than CI! Even if insurance paid for 1st CI, I can't afford a 2nd CI. Stem cells will give me improved hearing in both ears.

You would never be a candidate for CI since your good ear is normal and a transear(or BAHA) would be far better. Ive been researching CI vs. HA and studies show that CI matches HAs for those with severe hearing loss. If stem cells gives me 30db improvement, ill hear with HAs equal(if not better) to those with CI for speech. Well actually ill hear way better for environmental sounds though. (80db HL + 70db gain=10db aided) I have a thread on this in my blog and on this forum.

When my dad wakes up soon, ill show him this youtube video. There's dozens if not hundreds of genes related to hearing/deafness. I am not expecting to become hearing(not till I get a genetic cure), I am expecting to be less deaf or HOH after stem cells and with my HAs, get access to sounds/speech at around 10db HL. If prelingually deaf can adjust to CI, I am confident ill adjust great to stem cells.

Been a while since I saw you on alldeaf. When will you be on AIM messenger? Also for others reading this, id love to chat about stem cells in this thread, in my blog(link in sig) or on AIM messenger.

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deafdude1

I showed the youtube video to my dad:

Chloe, a student in California lost her hearing 3 years ago due to a cold. She got another cold and lost more hearing in the other ear. Her hearing loss became progressive. Her parents are doctors. They both work in a hospital and none of the doctors could restore her hearing initally. They believed the hearing loss is autoimmune related. She was fitted with the best HAs bilaterally(both ears) to amplify her residual hearing. Later on(3 years after she lost her hearing), the doctors discussed stem cells with Chloe's parents. It was assured that using her own stem cells was 100% safe even though it was experimental. She was a success case and no longer wears HAs. One ear is at 50% of normal and the other ear is at 90% of normal. Music sounds great, especially in her better ear. She is so happy to be able to hear again!

My comments: I can't find anything about converting % HL to db HL. I did find that the cutoff for normal hearing is 25db HL. So it's likley her good ear is hearing at 25-35db PTA and her bad ear is probably at 50-60db HL or a moderate HL. She could benefit from a HA in the bad ear, but chooses not to wear HAs. Her good ear is good enough that she hears plenty without needing HA. Someone will need to email that clinic or her parents and find out her before and after audiogram or at least what db was her loss before and after? Regardless, such a drastic improvement that hearing is functional without HAs gets me and my dad very excited! I look forward to the day of hearing better. I have realistic expectations as ive mentioned many times.

Her case serves as evidence that stem cells has the ability to regenerate hair cells NOW and give near normal unaided hearing! Not everyone will achieve an improvement as drastic as she and improvement may not be the same for both ears. It's possible if she got a 2nd round of stem cells, she could achieve additional improvements in her worse ear. Ive been reading stem cell studies on animals and while none get down to 0db perfect hearing, the improvements are huge and on the order of 30, 40, 50db! The animal studies show that the more residual hearing that is saved, the better your hearing will be. Those with plenty of residual hearing are getting down to near normal hearing which is on the order of 20-35db loss compared to their hearing before it was destroyed with sounds or ototoxins. I could get down to near normal hearing at 250Hz and below and in the mid and high frequencies, my hearing could be anywhere from 50db HL to 100db HL because I have virtually no residual hearing at 1000Hz and above. I plan to use transposition if I don't have enough high frequency hearing.

My chances of being able to get stem cells in the very near future are high. I am just waiting for more pioneers to have gone ahead and report their results. I want an idea of how much improvement to expect and also stem cell technology is moving fast, it surely will be better tomorrow than it's today. The evidence of stem cell's success is rapidly growing and I look forward to seeing more results by the other pioneers who are going ahead. I may decide to go ahead sometime in 2012, but could be much sooner depending how many pioneers are going to be getting stem cells in 2010(next year) and how great their results are.

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stemcellsdeaf

many thanks for the information and summarize what the video says.
We will continue to communicate!

faire_jour

DD,

Why is it better to have a 100db loss in the highs (which you claim is possible) than to be able to hear at 30db across all frequencies? I don't see how that is an improvement...

stemcellsdeaf

STEM CELLS HEAL HEARING LOSS
STEM CELLS HEAL HEARING LOSS The Stem Cell Blog

kokonut

Kokonut Pundit: Video Interview (caption) with first American to have her hearing loss restored

video (caption) interview of Chloe Sohl on her hearing loss restoration through the use of her own adult stem cells.

Lissa

Me neither. It is better to have a 30db across all frequencies.....

You would not be able to hear much not even with a 100db loss in the highs

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Proud to be deaf and a CI user!!

Lissa

She still had some hearing left....

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Proud to be deaf and a CI user!!

kokonut

She has regained more hearing. That's the key point.

deafdude1

The next step is for me to research the extent of how much stem cells can improve hearing. At this point, it's known that stem cells works on humans, is available now and the regenerated hair cells function great! I also have realistic expectations and will be happy with as little as 20db improvement.



30-40db improvement would get me to 0db in the lows and normal hearing in most frequencies. Ill hear environmental sounds similar to a hearing person and hear speech much better than CI, but still a little below that of a hearing person. My aided audiogram after stem cells could be better than what my dad hears unaided. If stem cells gets me to only 100db in the highs, ill just enable transposition to get me to better than 30db across.

I would be very surprised if stem cells gives me or most people enough hearing to not need HAs. Her results could be exceptional for all we know. We would need to see results from at least a dozen others to further determine the extent of the improvement. Ive researched the improvement in animal models and have come to the conclusion that the audiogram above reflects average improvement after stem cells. I would have a moderate to severe HL and be aided to normal dipping down to mild in the highest frequencies. This is a limitation of HA's gain.

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Lissa

Is even 0db possible????? Won't 0db be useless since that's no noise??
I know you said you want stem cells. But why pay all that money then find out they won't work for you. Why are you so desparate to hear? Hearing's not all that great. It's just hearing the world.

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Proud to be deaf and a CI user!!

deafdude1

0db does not mean no noise, just the threshold of "perfect" hearing. There are no guarantees in life. CI doesn't always work and stem cells don't always work either. If stem cells don't work, I still keep my residual hearing. I want to hear for the same reason you are getting CI to hear better. We discussed our choices. CI is your choice, stem cells are mine.

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webexplorer

I got your PM. I guess that's your thread here.

Are you flying to Korea for your surgery? The stem-cell was started at University of Washington. But, the original is from Virginia Merrill Bloedel Hearing Research Center. I think that you might want to read these links for yourself because it's in the U.S. It is nothing wrong with the foreign country... I found some of these links a couple of years ago, and the links are still active.

Home

https://depts.washington.edu/iscrm/r...generation.php

Do No Harm: The Coalition of Americans for Research Ethics

The biggest problem is that health industrials are stealing the money from the government's fund or someone's fund. Some of them do lie to us for many ways to make us believe that it works, or it causes a cancer, or even telling us that it does not work due twist the money situation. I want to avoid to write the long details here. No easy so we need to get a hard proof and look up a company's background information before you decide to get your surgery.

stemcellsdeaf

thank you very much!
You have done a great job. You see the video many people can not hear well, and the subtitle is a big job!

faire_jour

No responsible audiologist will aid you to 0 db. It just won't happen.

Plus, how bad do you think the highs will sound, cranked all the way up and full of distortion, if you are at a mild loss in the lows?

Lighthouse77

you know, my older sister is the same way. She told me she loves her hearing aids, and is against CI. Then later told me that She rather wait til stem cell come out.

I've come to conclusion that people who keep pushing stem cells are really anti-CI and they really doing it so people will delay CI longer (because hope is on the way!). Nothing wrong with that, but I've learned to take them a grain of salt (or whatever the saying is)

She even went as far as comparing a friend with CI to Hearing aids to see how much they can hear. Then she reported back it to me as CI is terrible thing.. and this was AFTER I have my CI. She is trying to get me to hate my CI or be anti-CI

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Good thing about standards is that there are so many of them to choose from.

stemcellsdeaf

"Stem Cell Treatment For Hearing Loss Has Begun".
Stem Cell Treatment For Hearing Loss Has Begun. Life Seen through Karen Mayes’ Eyes

sallylou

An article about commercial stem-cell clinics:

The Shady Side of Embryonic Stem Cell Therapy

Caveat Emptor.

Credible research is being done at universities. I know that a local medical school is conducting stem cell studies for heart disease (adult stem cells). It will be interesting to hear the results.

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Happy holidays!