Stem cell therapy may restore hearing to the totally deaf in 50 years

Miss-Delectable

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Stem cell therapy may restore hearing to the totally deaf in 50 years

A leading researcher at the Eye and Ear Hospital in Melbourne says that she is working on a technique that can restore hearing to the totally deaf in 50 years.

Researcher Bryony Coleman has revealed that she is carrying out the worlds first research into the potential of stem cells to regrow the nerves that connect the ear to the brain.

She says that the technique may help improve the quality of hearing in people with cochlear implants, and even restore hearing to those who are totally deaf, if her research turns out to be successful.

“Fifty years down the track this might be one of many techniques we might not even need a cochlear implant,” theage.com.au quoted her as saying.
When some of the tiny, vibrating hairs in the inner ear get damaged, each hair cell’’s destruction leads to the death of up to 10 nerves that carry sound information into the brain.

The cochlear implant can replace some of the work of the hair, but it cannot regrow the nerves.

Coleman believes that “precursor” cells that can grow into replacement nerve cells can offer a solution.

“The theory is that the bigger and healthier the nerves, the better the
cochlear implant will work. We are using stem cells to make that bigger and healthier,” she said.

She, however, admits that the procedure is more complicated than sticking a bunch of cells in your ear, for it would require growing the cells in the right place so that they connect the hair cell to the brain.

“We have transplanted stem cells into the (inner ear) and they survive, but we need to know if they work,” she said.

Scientists have already achieved success in regrowing the delicate hair cells of the inner ear of mice using gene therapy.

Coleman says that her work may supplement that breakthrough.
 
Fantastic!!! Hopefully medical technology will have also advanced so far that I can be fully transplanted into the body of an 18 year old and actually be young enough to have any use to the technique!!!:lol:

.....oh hang on......

if they can transplant me into a new body...they wouldn't need the stem cells in the new body to solve the hearing problem!!:roll:
 
I was reading some research the other day, and they are now discovering that stem cells are not accepted by the body without rejection, as was first believed would be possible. It now appears that the body treats the stem cells, in many cases, the same way it would any transplant...as a foreign substance. In order to prevent the body attacking the stem cells and rejecting them, it would be necessary for the recipient to take the anti-rejection drugs that suppress the natural immune system the same way any other organ recipient does.
 
Hmmmm. I wonder what the side effects are for the anti-rejection drugs, if any.
 
Hmmmm. I wonder what the side effects are for the anti-rejection drugs, if any.

There are many. Because they serve to suppress the immune system, they create a situation that any immune compromising disease creates. Reduced ability to fight off real disease, for one. A common cold quickly turns to life threatening pnuemonia, more susceptibility to certain forms of cancer, etc.
 
There are many. Because they serve to suppress the immune system, they create a situation that any immune compromising disease creates. Reduced ability to fight off real disease, for one. A common cold quickly turns to life threatening pnuemonia, more susceptibility to certain forms of cancer, etc.

Goodness, this must cause more problems for organ transplant recipients than I imagined! :eek3:
 
Goodness, this must cause more problems for organ transplant recipients than I imagined! :eek3:

Yes, and they must remain on the drugs for their entire life. If they stop taking them, their immune system will destroy the implanted organ. Organ transplantion is not without it very serious side effects.
 
I was reading some research the other day, and they are now discovering that stem cells are not accepted by the body without rejection, as was first believed would be possible. It now appears that the body treats the stem cells, in many cases, the same way it would any transplant...as a foreign substance. In order to prevent the body attacking the stem cells and rejecting them, it would be necessary for the recipient to take the anti-rejection drugs that suppress the natural immune system the same way any other organ recipient does.
is this true 100% of the time for 100% of the patients? Also can you cite the research paper you are referring to?
 
What about CI recipients? Do they require anti-rejection drugs? Are there any threads discussing this? Yeah, I plead almost total ignorance in this.
 
is this true 100% of the time for 100% of the patients? Also can you cite the research paper you are referring to?

You don't need the citation... it's a very commonly known medical fact. It's the problem that nearly all transplant patients have to deal with for rest of their lives. It is a bit rare to have a transplant with a complete compatibility (which means patients do not need to rely on drugs). That's why we're always always always trying to find a way to have transplant without having to rely on immo-suppression drugs. It's a very very long way to go but still one step closer...
 
What about CI recipients? Do they require anti-rejection drugs? Are there any threads discussing this? Yeah, I plead almost total ignorance in this.

no CI is not an organic implant. It is no different from having metal rods/plates drilled on your bones.
 
is this true 100% of the time for 100% of the patients? Also can you cite the research paper you are referring to?

Since stem cells are not being routinely used, there is no way of knowing whether it is true for 100% of recipients 100% of the time. That's why I said "in many cases". Especially when it comes to medicine, there will always be variance in individual response.

No, I can't cite the paper. I read it, retained the information, and went on to something else. It caught my attention, so I delved into it out of curiosity.
 
I have heard of the story couple years ago about the new future of CI/HA. It is based on MEMS (ultra-tiny chips) and/or nanotechnology that will be implanted directly inside your ear that will substitute as ear nerve. As long as your ear drum's functional, this process can work. In my case - my ears are perfectly functional except ear nerves. I have much lesser number of ear nerves than normal which is why I can barely hear only 120+ decibels without HA. For that kind of medical case - CI-MEMS is a perfect tool for it. It's basically HA/CI inside your ear. Future CI/HA will be based on nanotechnology and MEMS. The more money being put in this research, the faster it will become a reality. So far... the budget allocated for this type of research is meager. :mad2:

This is a more possible solution in nearer future than stem cell solution. Google keyword search: MEMS Hearing Aids
 
I have heard of the story couple years ago about the new future of CI/HA. It is based on MEMS (ultra-tiny chips) and/or nanotechnology that will be implanted directly inside your ear that will substitute as ear nerve. As long as your ear drum's functional, this process can work. In my case - my ears are perfectly functional except ear nerves. I have much lesser number of ear nerves than normal which is why I can barely hear only 120+ decibels without HA. For that kind of medical case - CI-MEMS is a perfect tool for it. It's basically HA/CI inside your ear. Future CI/HA will be based on nanotechnology and MEMS. The more money being put in this research, the faster it will become a reality. So far... the budget allocated for this type of research is meager. :mad2:

This is a more possible solution in nearer future than stem cell solution. Google keyword search: MEMS Hearing Aids

Unfortunately, it is difficult to get funding for a procedure that will have limited application. Stem cell research gets a large amount of funding because the findings can be applied across a wide variety disorders.
 
I was reading some research the other day, and they are now discovering that stem cells are not accepted by the body without rejection, as was first believed would be possible. It now appears that the body treats the stem cells, in many cases, the same way it would any transplant...as a foreign substance. In order to prevent the body attacking the stem cells and rejecting them, it would be necessary for the recipient to take the anti-rejection drugs that suppress the natural immune system the same way any other organ recipient does.

I believe a person can bypass the anti-rejection drugs if he got the organ from his identical twin.
 
I believe a person can bypass the anti-rejection drugs if he got the organ from his identical twin.

good question. my answer is - "not always." nature's a funny thing
 
What about CI recipients? Do they require anti-rejection drugs? Are there any threads discussing this? Yeah, I plead almost total ignorance in this.

CI is not an organ or transplant surgery of any form.
 
You don't need the citation... it's a very commonly known medical fact. It's the problem that nearly all transplant patients have to deal with for rest of their lives. It is a bit rare to have a transplant with a complete compatibility (which means patients do not need to rely on drugs). That's why we're always always always trying to find a way to have transplant without having to rely on immo-suppression drugs. It's a very very long way to go but still one step closer...
While I appreciate your response please dont' tell me what I don't need. Your points about transplant patients are not what I was seeking.
 
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