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I dont think its Alzheimers...this disease is something to do with
memory loss. I think your 21 year old cat is just old, 21 is really
old for a cat. Its mostly age related that she is not eating, she is
losing appetite and possibly because of the tumor.
My dad had a 16 year old Siamese cat that just lost his appetite,
he would not eat or drink..not even his favorite dish..tuna fish..he
loved that so much! So we took him to the vet and found out that
he had a tumor in his stomach that was so large. The vet said it could
not be removed. There was nothing he could do for him so had to put
to sleep so he would not suffer...it was sooo heartbreaking!
We did not want Jasper to suffer anymore ..so we had to say goodbye
to him then i saw the twinkle in his eye like its okay......Jasper knew
it was time.................oh well....*snifflin*........
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Im not deaf, just ignoring you! 
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